Biotech & Deep Tech Platform Company · AMTZ, Visakhapatnam

Turning clinical insight into manufacturable science.

Akrivis Health Care builds the materials, devices, and biological systems that the next decade of medicine will need. Our platforms span synthetic exosome-mimetic therapeutics, catechol-melanin tissue adhesives, and marine haemoglobin oxygenation systems — engineered in India, designed for the world.

3+
Active Platforms
Compounding scientific capability
5
Patents Filed
Multi-jurisdiction coverage
3
Certifications
CDSCO · ISO · State FDA, UKAS
15
Commercial Products
CDSCO-approved

We build platforms, not products. Each product is the expression of a platform; each platform is a body of knowledge that compounds.

Dr. Sarat Babu Janipalli

·

Founder & Managing Director

Science & Platforms

Five platforms. Each a body of knowledge that compounds.

Akrivis organises its work into platforms — not products. A platform is a body of knowledge, intellectual property, and manufacturing capability that can yield several products. The platform story is what makes Akrivis a deep tech company rather than a contract manufacturer.

Exosome-mimetic nano-vesicle cross-section showing lipid bilayer, ion channels, GPCR signalling pathways, mRNA/siRNA/tRNA cargo, IgG binding, and glycocalyx detail

SynExo™ Synthetic Exosome-Mimetic Nano-Vesicle — Structural ArchitectureHover or tap the markers to explore each component

TympanoSeal™ NeoTympanum — catechol-melanin tissue adhesive applied to a perforated tympanic membrane via a minimally invasive in-clinic procedure, showing the ear canal cross-section with cochlea and ossicles

TympanoSeal™ NeoTympanum — Non-Invasive Tympanic Membrane RepairCatechol-melanin bioadhesive on PLA scaffold, activated by pulsed 9.0 J/cm² light

FIRST-IN-CLASS DEVICE

Catechol-Melanin Adhesion

TympanoSeal™ NeoTympanum

Dual-mechanism tissue adhesive exploiting mussel-inspired catechol bioadhesion paired with the Raper–Mason melanin pathway. Lyophilised seven-component formulation on a PLA scaffold, activated by pulsed 9.0 J/cm² light. The world’s first non-invasive alternative to tympanoplasty surgery — a fifteen-minute in-clinic procedure targeting the 10M+ Indians affected annually.

First-in-class globally — no non-invasive alternative exists
Dual-mechanism: FMN-catechol + melanogenesis adhesion
Lyophilised seven-component formulation with scalable manufacturing
15-minute in-clinic procedure — targeting 10M+ patients annually
Validation Stage
CORE PLATFORM

SynExo™ Therapeutics

Synthetic Exosome-Mimetic Nano-Vesicles

Synthetic bioactive peptides (copper tripeptide, palmitoyl pentapeptide) encapsulated in exosome-mimetic nano-vesicles (30–150 nm). Mimics natural exosome regenerative signalling without live-cell complexity. The synthetic peptide backbone carries an established CDSCO safety profile, enabling an accelerated regulatory pathway.

Multi-source: synthetic, plant, animal, hybrid, lab-expressed
cGMP manufacturing at AMTZ, Visakhapatnam
CDSCO accelerated regulatory pathway
Five source types — broadest platform in India
Commercial (cosmeceuticals) → Validation (therapeutics)
COSMECEUTICAL + THERAPEUTIC

EXOGLAM

Exosomes & Plant-Derived Exosome-Like Nanoparticles

Therapeutic and cosmetic formulations built on exosomes and plant-derived exosome-like nanoparticles (PELNs). Applications span aesthetic medicine, wound repair, and adjacent regenerative indications. European market access strategy supports international expansion.

Dual-track: cosmeceutical (commercial) + therapeutic (pipeline)
European market access pathway established
PELN platform licensed to international partners
Expanding global distribution network
Commercial (cosmeceuticals) + Pipeline (therapeutics)
INTERNATIONAL PARTNERSHIP

HEMOSOME OxyRescue Serum

Marine Haemoglobin — Hemarina SA, France

Commercialisation of the OXYMARIS / Hemosome technology developed by Hemarina SA of France. Marine haemoglobin extracted from Arenicola marina carries oxygen across mammalian biological systems. Topical oxygenation applications in wound healing and aesthetic medicine.

Exclusive partnership with Hemarina SA, France
Marine haemoglobin — unique biological mechanism
Wound healing + aesthetic medicine applications
Arenicola marina-derived oxygen carrier technology
Partnership Active
EMERGING PLATFORMS

ClearSight Nano · Nano Collagen · VOC · MPTR

Nanomaterials, Diagnostics & Epigenetic Reprogramming

ClearSight Nano: nanomaterials platform with optical applications. Nano Collagen: exclusive supply with Holista Colltech (ASX: HCT), signed December 2025. VOC breathalyzer: diagnostic device exploiting volatile organic compound signatures. MPTR: autologous epigenetic reprogramming delivering Yamanaka factors via targeted nanoparticle systems.

Holista Colltech (ASX: HCT) exclusive supply agreement
VOC breathalyzer — non-invasive diagnostic platform
MPTR — 12-chapter technical record, Yamanaka factor delivery
ClearSight Nano — optical nanomaterials
Various stages of development
Portfolio & Pipeline

From validated cosmeceuticals to therapeutic pipeline.

A validated cosmeceutical portfolio supports the development of regenerative therapeutics and first-in-class medical devices. Each product leads with the clinical problem it solves, followed by the mechanism, then the evidence, then the development stage.

Therapeutic Pipeline

SynExo wound healing gel product

SynExo™ Wound Gel

Chronic & acute wound healing

Exosome-mimetic nano-vesicles delivering copper tripeptide + palmitoyl pentapeptide

Pre-clinical
CDSCO regulatory pathwayPre-clinical validation
SynExo burn treatment gel product

SynExo™ Burn Gel

Partial-thickness burn management

Nano-vesicle encapsulated regenerative peptides for dermal remodelling

Pre-clinical
CDSCO regulatory pathwayPre-clinical validation
TympanoSeal ENT medical device

TympanoSeal™ NeoTympanum

Tympanic membrane perforation repair

FMN–catechol cross-linking + Raper–Mason melanogenesis on PLA scaffold

Validation
CDSCO medical device pathwayValidation stage
Akrivis commercial cosmeceutical products
Premium cosmeceutical serums

Commercial Portfolio

EXOGLAM Serums

Aesthetic Medicine

Commercial

CDSCO-Approved

Nano Collagen Range

Dermal Remodelling

Commercial

Holista Colltech (ASX: HCT) Exclusive Supply

HEMOSOME OxyRescue

Topical Oxygenation

Validation

Hemarina SA Partnership

SynExo™ Hair Growth

Trichology

Commercial

CDSCO-Approved

SynExo™ Anti-Ageing

Cosmeceutical

Commercial

CDSCO-Approved

Company & Leadership

Built by scientists, scaled by operators.

Seven founders and directors with 85+ combined years across nanomaterials, clinical research, regulatory affairs, international business development, and strategic finance.

Dual-Entity Structure

Akrivis Health Care Private Limited is the commercial operating entity — manufacturing, sales, and distribution. HCRB (Human Cell Research Bharat) is the IP vault and R&D entity that owns the patent portfolio and licenses technology to Akrivis. This structure separates commercial risk from intellectual property.

SJ

Dr. Sarat Babu Janipalli

Founder & Managing Director

ScienceSurgeon-scientist. Systems-thinker. Builder.

Clinical to formulation to systems — scientist with two decades of experience in surgery with interests in nanomaterials and regenerative medicine. Leads platform architecture, IP strategy, and regulatory navigation. Architect of the SynExo™ manufacturing process.

VI

Dr. Vamshi Krishna Irlapati

Co-Founder & Chief Scientific Officer

SciencePhD (Biotechnology)

Leads pre-clinical research, assay development, and scientific validation across all six platforms. Translates platform science into reproducible manufacturing protocols and regulatory-grade documentation.

RE

Mr. Ravi Eswarapu

Co-Founder & Chief Business Officer

BusinessMBA, 20+ Years in Strategic Business Development

Drives commercial strategy, international partnerships, and investor relations. Architect of the B2B distribution network spanning India, Europe, and the Middle East.

SK

Mr. Sampath Kumar Janipalli

Founder — International Operations

OperationsInternational Operations & Supply Chain

Manages international operations, entity coordination, and cross-border supply chain logistics. Anchors European distribution and partnership infrastructure.

AS

Mr. Abhijit Samant

Director — Regulatory Affairs & Quality Systems

RegulatoryRegulatory Affairs Specialist

Oversees CDSCO submissions, ISO compliance, and quality management systems across the AMTZ manufacturing facility. Navigates accelerated regulatory pathways for therapeutic approvals.

KS

Mr. Kuldeep Singh

Director — Manufacturing & Supply Chain

OperationsOperations & Manufacturing Leadership

Leads manufacturing operations at the AMTZ facility, supply chain optimisation, and production scaling. Maintains cGMP compliance and quality standards across the commercial portfolio.

MC

CA (Dr.) Mahaveer Chaplot

Founder — Private Equity & Strategic Finance

FinanceChartered Accountant, JITO Apex Secretary (2024–26)

Prominent Chartered Accountant, educator, and community leader with over two decades of expertise in private equity, banking, and agripreneurship. Director of Agribid, an AI-driven platform empowering farmers. General Secretary of the Certified Accountants Division, International Council of Jurists. Currently serving as Sachiv (Secretary) for JITO Apex (2024–26).

Regulatory & Quality

Compliance is infrastructure, not a checkbox.

Akrivis maintains active certifications across Indian and international regulatory frameworks. The AMTZ facility in Visakhapatnam serves as the manufacturing anchor, operating under cGMP protocols with continuous quality monitoring.

CDSCO

Active

Central Drugs Standard Control Organisation

Manufacturing licence for cosmeceutical and therapeutic formulations. Accelerated regulatory pathway for synthetic peptide-based therapeutics. Full commercial portfolio approved.

ISO 22716:2007

Certified

Cosmetics GMP

Good Manufacturing Practice for cosmetic products. Covers the AMTZ facility production lines for the entire EXOGLAM and SynExo™ cosmeceutical portfolio.

ISO 9001:2015

Certified

Quality Management Systems

Organisation-wide quality management system certification covering design, development, manufacturing, and distribution of cosmeceutical and therapeutic products.

US FDA

Registered

United States Food & Drug Administration

Facility registration and product listing for export-grade cosmeceutical formulations. Enables direct export through registered distribution channels.

BIS MHD-20

Institutional Member

Bureau of Indian Standards — Medical & Healthcare Devices

Institutional membership on the MHD-20 committee. Akrivis participates in drafting Indian standards for exosome-based products and medical devices. This is an institutional credential.

TÜV Rheinland

Validated

Independent Elemental Validation

Independent third-party validation of platform materials via Inductively Coupled Plasma Mass Spectrometry. Confirms elemental composition and purity across the SynExo and EXOGLAM portfolios.

Manufacturing Anchor: AMTZ, Visakhapatnam

The Andhra Pradesh MedTech Zone (AMTZ) is Asia's first integrated medical device manufacturing ecosystem. Akrivis operates its cGMP facility within AMTZ, providing access to shared analytical infrastructure, regulatory support, and a cluster of complementary medical device manufacturers. The facility handles formulation, filling, packaging, and quality control for the entire commercial portfolio and therapeutic pipeline.

Akrivis cGMP manufacturing facility at AMTZ, Visakhapatnam
Partnerships & Distribution

Engineered in India, partnered globally.

Strategic partnerships with European and Australian biotech companies provide access to proprietary biological materials, international distribution channels, and regulatory expertise. Commercial B2B relationships span India, the UK, Canada, and the Middle East.

Global partnership network spanning India, France, Australia, United Kingdom, Canada, and Malaysia
International scientific collaboration between researchers

Strategic & Technology Partners

Hemarina SA

Morlaix, France

Marine haemoglobin partnership for HEMOSOME OxyRescue Serum. Arenicola marina-derived oxygen carrier for topical wound healing and aesthetic medicine applications.

Technology partnership

Holista Colltech

ASX: HCT, Australia

Exclusive supply agreement for Nano Collagen platform. ASX-listed biotech specialising in collagen extraction and nanomaterials.

Exclusive supply agreement

Commercial & Distribution Partners

Elegantes London / Harrods UK

United Kingdom

B2B Distribution

SkinSeqnc Canada

Canada

B2B Distribution

Define Bio

India

Subsidiary

Nano-Malaysia

Malaysia

Partner

Human Cell Research Bharat

India

Research and Ideation Channel

AMTZ Ecosystem Partners

Visakhapatnam, India

Manufacturing Ecosystem
Get in Touch

Connect with Akrivis.

Whether you are an investor, potential partner, researcher, or member of the press, we welcome the opportunity to discuss how Akrivis platforms can create value together.

Professional biotech boardroom setting

IP Portfolio

8
Patents Filed
Multi-jurisdiction coverage
5+
Platforms
Deep tech portfolio
33
Patent Claims
Across key platforms
4
Certifications
CDSCO · ISO · State FDA, UKAS

Send an Inquiry

Reach out directly to the Akrivis leadership team for investment discussions, partnership opportunities, research collaborations, or media inquiries.